ADAM33 haplotypes are associated with asthma in a large Australian population
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چکیده
منابع مشابه
ADAM33 gene polymorphisms in Southwestern Iranian patients with asthma
Objective(s): Asthma, the most frequent chronic respiratory disease, results from a complex interaction between multiple genes and environmental factors. To date, more than 100 candidate genes and single nucleotide polymorphisms (SNPs) have been reported to be associated with asthma. One of the discovered genes related to asthma is ADAM33. However, the relationship between ADAM33 gene polymorph...
متن کاملADAM33 polymorphisms are associated with asthma and a distinctive palm dermatoglyphic pattern
A close correlation between asthma and palm dermatoglyphic patterns has been observed in previous studies, but the underlying genetic mechanisms have not been investigated. A disintegrin and metalloprotein‑33 (ADAM33) polymorphisms are important in the development of asthma and other atopic diseases. To investigate the underlying mechanisms of the association between asthma and distinctive palm...
متن کاملADAM33 Polymorphisms Are Associated with Susceptibility to Systemic Lupus Erythematosus in a Korean Population
Received:May 18, 2015, Revised:(1st) August 5, 2015, (2nd) October 23, 2015, Accepted:October 23, 2015 Corresponding to:Seung-Cheol Shim, Division of Rheumatology, Department of Medicine, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon 35015, Korea. E-mail:[email protected] *The first two authors contributed equally to...
متن کاملContribution of ADAM33 polymorphisms to the population risk of asthma.
BACKGROUND ADAM 33 is the first gene identified as a candidate for asthma by positional cloning techniques, with association studies reaching impressive statistical significance. It has a postulated role in myogenesis, airway modelling, and signalling via protein shedding. Concerns over the methodology of the initial study have led to several attempts at replication, with inconsistent results. ...
متن کاملAssociation of ADAM33 gene polymorphisms with allergic asthma
Objective(s): Asthma results from the interaction between genetic and environmental factors. ADAM33 gene on chromosome 20p13 is associated with asthma and airway hyperresponsiveness. Materials and Methods: This is a case-control study, where four SNPs S1 (rs3918396), T1 (rs2280091), T2 (rs2280090), V4 (rs2787094) of ADAM33 gene have been assessed in patients with allergic asthma and normal con...
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ژورنال
عنوان ژورنال: European Journal of Human Genetics
سال: 2006
ISSN: 1018-4813,1476-5438
DOI: 10.1038/sj.ejhg.5201662